DEMO: Enable Zero-Day Malware Protection
Start course

This course shows how to set up Microsoft Defender for Microsoft 365 through a series of practical demonstrations from the Microsoft 365 platform. You will learn about some general cybersecurity practices before being shown how Microsoft Defender can help you implement them.

Learning Objectives

  • Understand how to protect against phishing, malware, and spam using Microsoft Defender
  • Learn about safe links and safe attachments and configure them
  • Learn how to enable zero-day malware protection

Intended Audience

This course is intended for those who wish to learn how to configure protection in Microsoft Defender for Office 365.


To get the most out of this course, you should have a basic understanding of Microsoft 365.


Hello and welcome back. So what we're gonna do here in this demonstration is just walk through the process real quickly of enabling essentially what is Zero-Day Protection in Office 365 apps. Now on the screen here, I'm logged into my Office 365 security compliance portal, I'm logged in as the Global Admin.

To get to our protection for Defender, we're gonna drop down into Threat Management and then what we can do here, we can go to Policy or we can go to Dashboard. If we go to Policy here and then we select Safe Attachments, what we can do is select Global Settings and then enable our global settings for attachments in SharePoint, OneDrive and Teams.

Now, if we close this out and go to the dashboard, we can see up top here how we protected your organization in my default dashboard and right under Configure Safe Attachments, we also have the option here to configure safe attachments to protect against Zero-day malware. So what we'll do here is we'll select this option and this is really gonna be quick.

We'll bounce into Global Settings and then what we do here is turn on Defender for Office 365 for SharePoint, OneDrive and Teams. And what this does is protect the files in SharePoint, OneDrive and Teams. Essentially, if it finds a file and it's identified as malicious Safe Attachments will prevent users from opening or downloading the file. And then this second option here applies if we have a Microsoft 365 E5 or Microsoft 365 E5 security license. I don't think I have any five offhand, but let's see if I can turn it on just so I can show you. And now here we have this last option that allows us to allow users to click through the protective view even if safe documents identified a file is malicious. This is turned off by default.

Essentially, this is our way of telling the policies here or the global settings, whether or not we wanna allow our users to click through if a file is identified as malicious. We're not gonna turn that on. So we'll go ahead and save it. As now, if we go back into global settings, we can see our settings are turned on. And so that is how you protect your organization from malicious content, in email attachments and in files in SharePoint, OneDrive and Microsoft Teams.

About the Author
Learning Paths

Tom is a 25+ year veteran of the IT industry, having worked in environments as large as 40k seats and as small as 50 seats. Throughout the course of a long an interesting career, he has built an in-depth skillset that spans numerous IT disciplines. Tom has designed and architected small, large, and global IT solutions.

In addition to the Cloud Platform and Infrastructure MCSE certification, Tom also carries several other Microsoft certifications. His ability to see things from a strategic perspective allows Tom to architect solutions that closely align with business needs.

In his spare time, Tom enjoys camping, fishing, and playing poker.